Study of prevalence of thyroid peroxidase antibodies in preterm deliveries and recurrent pregnancy loss

Background: Evaluation of thyroid disorder in pregnancy is essential for maternal health, obstetrical outcome and neurodevelopment the child. Euthyroid pregnant women having positive peroxidase antibodies have an elevated risk miscarriage, premature birth, gestational hypertension, intrauterine fetal demise. Thyroid autoimmunity (TAI) subclinical hypothyroidism (SCH) been connected with adverse outcomes foetus. The present aim study was to estimate prevalence TPO recurrent losses, first trimester abortions preterm deliveries.Methods: This a hospital-based cross-sectional conducted 18 months. consists 100 who had deliveries miscarriages attending department obstetrics gynaecology, Narayana medical college hospital, Nellore, Andhra Pradesh.Results: In our out cases, 11 high antibody (TPOAb) levels, which 9 2 miscarriages. Out cases 5 T3 6 T4 levels 24 TSH levels.Conclusions: There statistically significant association T3, T4, and, (P<0.05) it leads developing during pregnancy. presence TPOAb significantly increases delivery. screening avoid complications. So, are